Buy 25I-NBOMe 500g online
25I-NBOMe 500g (2C-I-NBOMe, Cimbi-5, Smiles and also shortened to “25I“) is a novel synthetic psychoactive substance with strong hallucinogenic properties, synthesized in 2003 for research purposes. Since 2010, it has circulated in the recreational drug scene, often misrepresented as LSD. The recreational usage of 25I is associated with severe intoxication and deaths in humans. 25I-NBOMe 500g for sale
25I-NBOMe 500g was synthesized for biochemistry research to map the brain’s usage of the type 2A serotonin receptor. A derivative of the substituted phenethylamine 2C-I family, it is the most well-known member of the 25-NB family. It was discovered in 2003 by chemist Ralf Heim at the Free University of Berlin, who published his findings in his PhD dissertation. The compound was subsequently investigated by a team at Purdue University led by David Nichols. Where to buy 25I-NBOMe 500g online usa.
The carbon-11 labelled version of 25I-NBOMe, [11C]Cimbi-5, was synthesized and validated as a radiotracer for positron emission tomography (PET) in Copenhagen. Being the first 5-HT2A receptor full agonist PET radioligand, [11C]CIMBI-5 shows promise as a more functional marker of these receptors, particularly in their high affinity states.
Recreational use for 25I-NBOMe 500g
Although 25I-NBOMe 500 was discovered in 2003, it did not emerge as a common recreational drug until 2010, when it was first sold by vendors specializing in the supply of designer drugs. In a slang context, the name of the compound is often shortened to “25I” or is simply called “N-Bomb”. According to a 2014 survey, 25I-NBOMe 500g was the most frequently used of the NBOMe series. By 2013, case reports of 25I-NBOMe 500 intoxication, with and without analytic confirmation of the drug in the body, were becoming increasingly common in the medical literature.
25I-NBOMe 500g is widely rumored to be orally inactive; however, apparent overdoses have occurred via oral administration. Common routes of administration include sublingual, buccal, and intranasal. For sublingual and buccal administration, 25I-NBOMe 500g is often applied to sheets of blotter paper of which small portions (tabs) are held in the mouth to allow absorption through the oral mucosa. There are reports of intravenous injection of 25I-NBOMe 500g solution and smoking the drug in powdered form.
Due to its potency and much lower cost than so-called classical or traditional psychedelics, 25I-NBOMe 500g blotters are frequently misrepresented as, or mistaken for, LSD blotters. Even small quantities of 25I-NBOMe 500g can produce a large number of blotters. Vendors would import 25I-NBOMe 500g in bulk (e.g., 1 kg containers) and resell individual doses for a considerable profit.
Dosage for 25I-NBOMe 500g
25I-NBOMe 500g is potent, being active in sub-milligram doses. A common dose of the hydrochloride salt is 600–1,200 μg. The UK Advisory Council on the Misuse of Drugs states that a common dose is between 50 and 100 μg, although other sources indicate that these figures are incorrect; Erowid tentatively suggests that the threshold dosage for humans is 50–250 μg, with a light dose between 200–600 μg, a common dose at 500–800 μg, and a strong dose at 700–1500 μg.
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